Skip to main content

Using Artificial Intelligence to Assess Ulcerative Colitis

Researchers from Tokyo Medical and Dental University (TMDU) have developed an artificial intelligence system that effectively evaluates endoscopic mucosal findings from patients with ulcerative colitis without the need for biopsy collection.

Assessments of patients with ulcerative colitis (UC), which is a type of inflammatory bowel disease, are usually conducted via endoscopy and histology. But now, researchers from Japan have developed a system that may be more accurate than existing methods and may reduce the need for these patients to undergo invasive medical procedures.
In a study published this February in Gastroenterology, researchers from Tokyo Medical and Dental University (TMDU) have revealed a newly developed artificial intelligence (AI) system that can evaluate endoscopic findings of UC with an accuracy equivalent to that of expert endoscopists.

Accurate evaluations are critical in providing optimal care for patients with UC. Previous studies have indicated that both endoscopic remission, evaluated via assessment of endoscopic procedure, and histological remission, as indicated by the degree of microscopic inflammation, can predict patient outcomes, and are thus frequently used as treatment goals. However, intra- and inter-observer variations occur in both endoscopic and histological analyses, and histological analysis frequently requires the collection of tissue via biopsies, which are invasive and costly.
"The interpretation of endoscopic images is subjective and based on the experience of individual endoscopists, thereby making the standardization of evaluation and real-time characterization challenging," says lead author of the study Kento Takenaka. "To address this, we sought to develop a deep neural network (DNN) system for consistent, objective, and real-time analysis of endoscopic images from patients with UC (DNUC)."
To do this, the researchers developed a system with DNNs to evaluate endoscopic images from patients with UC. DNNs are a type of AI machine-learning method that are based on the construction of artificial neural networks.
"We constructed the DNUC algorithm, using 40,758 images of colonoscopies and 6885 biopsy results from 2012 patients with UC," says senior author Mamoru Watanabe. "This comprised the training set for machine-learning, which enabled the algorithm to learn to accurately evaluate and classify the data."
The researchers then validated the accuracy of the DNUC algorithm using 4187 endoscopic images and 4104 biopsy specimens from 875 patients with UC.
"We found that the DNUC achieved a level of accuracy that was equivalent to that of expert endoscopists," says Takenaka. "Thus, our system was able to predict histologic remission from UC using endoscopic images only, as opposed to both histological and endoscopic data. This represents an important development given the costs and risks associated with biopsies."
The DNUC may be able to identify UC patients who are in remission without requiring them to undergo biopsy collection and analysis. This could save time and money for medical institutions, and limit exposure to invasive medical procedures for individuals with UC.

For more details kindly contact:

Alexia Roy | Larix International Pte Ltd
URL: https://larixconferences.com/gastroenterology
E: gastro@gastroenterologyconferences.com
WhatsApp: +65 3158 6820
Contact: +65 31655042

Comments

Post a Comment

Popular posts from this blog

Healthy child makes healthy Nation Functional gastrointestinal disorders are common in children and adolescents with complaints of abdominal pain. The most common pediatric functional GI condition is functional abdominal pain. Children with this disorder usually experience recurrent pain in the middle of the abdomen. When the abdominal pain or discomfort is relieved by stooling or is connected with a change in the frequency or consistency of the stool, we call that irritable bowel syndrome (IBS). Patients with this condition can have mucus (but not blood) in the stool and feel and look bloated. When the pain is in the upper abdomen and not related to stool changes, the term “functional dyspepsia” is used. If the child is taking medications called “NSAIDs” also known as NSAID medications, it may be reduce the pain. Treatments for functional gastrointestinal disorders differ based on what symptom is affecting the patient the most. Parenteral nutrition may be prescribed for c...
3 comments
Read more
Common Digestive Disorders Gastroesophageal Reflux Disease (GERD)  Heartburn happens, but if it occurs regularly, you may need to be evaluated for  GERD . A medical provider can often diagnose GERD based on a description of symptoms alone, but if the problem has been ongoing for some time, additional diagnostic testing may be necessary to evaluate if the disease has caused damage to the esophagus. GERD most often presents as heartburn, but uncontrolled GERD can erode the lining of the esophagus and lead to bleeding. The condition can also cause pain in the chest so extreme that it is sometimes mistaken for a heart attack. Controlling GERD usually begins with simple lifestyle changes, including avoiding food for at least two hours before bedtime. Over-the-counter remedies can also provide some short-term relief for occasional heartburn, but for chronic or serious GERD, a prescription medication or even surgery may be necessary. Chronic Diarrhea Diar...
Post a Comment
Read more